Scientific Publications

Rs964184 (APOA5-A4-C3-A1) Is Related to Elevated Plasma Triglyceride Levels, but Not to an Increased Risk for Vascular Events in Patients with Clinically Manifest Vascular Disease.

Publication TypeJournal Article
Authorsvan de Woestijne, AP, van der Graaf Y., de Bakker PI, Asselbergs FW, Spiering W., Visseren FL, and SMART Study Group
AbstractSingle nucleotide polymorphisms in the APOA5-A4-C3-A1 gene complex are associated with elevated plasma triglycerides and elevated vascular risk in healthy populations. In patients with clinically manifest vascular disease, hypertriglyceridemia and metabolic syndrome are frequently present, but the contribution of these single nucleotide polymorphisms to plasma triglycerides, effect modification by obesity and risk of recurrent vascular events is unknown in these patients.
Year of Publication2014
JournalPloS one
Date Published (YYYY/MM/DD)2014/01/01