|Publication Type||Journal Article|
|Year of Publication||2014|
|Authors||van de Woestijne, AP, van der Graaf, Y, de Bakker, PI, Asselbergs, FW, Spiering, W, Visseren, FL, SMART Study, G|
Single nucleotide polymorphisms in the APOA5-A4-C3-A1 gene complex are associated with elevated plasma triglycerides and elevated vascular risk in healthy populations. In patients with clinically manifest vascular disease, hypertriglyceridemia and metabolic syndrome are frequently present, but the contribution of these single nucleotide polymorphisms to plasma triglycerides, effect modification by obesity and risk of recurrent vascular events is unknown in these patients.