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The lancet. Diabetes & endocrinology DOI:10.1016/S2213-8587(14)70113-5

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.

Publication TypeJournal Article
Year of Publication2014
AuthorsVimaleswaran, KS, Cavadino, A, Berry, DJ, investigators LifeLines Cohort Study, , Jorde, R, Dieffenbach, AK, Lu, C, Alves, AC, Heerspink, HJ, Tikkanen, E, Eriksson, J, Wong, A, Mangino, M, Jablonski, KA, Nolte, IM, Houston, DK, Ahluwalia, TS, van der Most, PJ, Pasko, D, Zgaga, L, Thiering, E, Vitart, V, Fraser, RM, Huffman, JE, de Boer, RA, Schöttker, B, Saum, KU, McCarthy, MI, Dupuis, J, Herzig, KH, Sebert, S, Pouta, A, Laitinen, J, Kleber, ME, Navis, G, Lorentzon, M, Jameson, K, Arden, N, Cooper, JA, Acharya, J, Hardy, R, Raitakari, O, Ripatti, S, Billings, LK, Lahti, J, Osmond, C, Penninx, BW, Rejnmark, L, Lohman, KK, Paternoster, L, Stolk, RP, Hernandez, DG, Byberg, L, Hagström, E, Melhus, H, Ingelsson, E, Mellström, D, Ljunggren, O, Tzoulaki, I, McLachlan, S, Theodoratou, E, Tiesler, CM, Jula, A, Navarro, P, Wright, AF, Polasek, O, International Consortium for Blood Pressure, (ICBP), consortium Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), , consortium Global Blood Pressure Genetics (Global BPGen), , Caroline, H, Wilson, JF, Rudan, I, Salomaa, V, Heinrich, J, Campbell, H, Price, JF, Karlsson, M, Lind, L, Michaëlsson, K, Bandinelli, S, Frayling, TM, Hartman, CA, Sørensen, TI, Kritchevsky, SB, Langdahl, BL, Eriksson, JG, Florez, JC, Spector, TD, Lehtimäki, T, Kuh, D, Humphries, SE, Cooper, C, Ohlsson, C, März, W, de Borst, MH, Kumari, M, Kivimaki, M, Wang, TJ, Power, C, Brenner, H, Grimnes, G, van der Harst, P, Snieder, H, Hingorani, AD, Pilz, S, Whittaker, JC, Järvelin, MR, Hyppönen, E
JournalThe lancet. Diabetes & endocrinology
Date Published2014/06/25
ISSN2213-8587
Abstract

Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25(OH)D concentration is causally associated with blood pressure and hypertension risk.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S2213-8587(14)70113-5
DOI10.1016/S2213-8587(14)70113-5
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/24974252?dopt=Abstract