< Back to Publications
Dopamine genetic risk score predicts depressive symptoms in healthy adults and adults with depression.
|Publication Type||Journal Article|
|Authors||Pearson-Fuhrhop, KM, Dunn EC, Mortero S., Devan WJ, Falcone GJ, Lee P., Holmes AJ, Hollinshead MO, Roffman JL, Smoller JW, Rosand J., and Cramer SC|
|Abstract||Depression is a common source of human disability for which etiologic insights remain limited. Although abnormalities of monoamine neurotransmission, including dopamine, are theorized to contribute to the pathophysiology of depression, evidence linking dopamine-related genes to depression has been mixed. The current study sought to address this knowledge-gap by examining whether the combined effect of dopamine polymorphisms was associated with depressive symptomatology in both healthy individuals and individuals with depression.|
|Year of Publication||2014|
|Date Published (YYYY/MM/DD)||2014/01/01|