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'Lnc'-ing enhancers to MYC regulation.
|Publication Type||Journal Article|
|Authors||Younger, ST, and Rinn JL|
|Abstract||Long noncoding RNAs (lncRNAs) are emerging as important functional components in the establishment of long-range chromosomal interactions. In a recent paper published in Cell Research, Xiang et al. provide mechanistic insight into this phenomenon by characterizing the role of CCAT1-L, a colorectal cancer-specific lncRNA, in intra-chromosome looping between the MYC gene promoter and distal upstream enhancer elements that regulate MYC transcription.|
|Year of Publication||2014|
|Date Published (YYYY/MM/DD)||2014/04/29|