You are here

Biological psychiatry DOI:10.1016/j.biopsych.2013.10.028

Rare Copy Number Variation in Treatment-Resistant Major Depressive Disorder.

Publication TypeJournal Article
Year of Publication2014
AuthorsO'Dushlaine, C, Ripke, S, Ruderfer, DM, Hamilton, SP, Fava, M, Iosifescu, DV, Kohane, IS, Churchill, SE, Castro, VM, Clements, CC, Blumenthal, SR, Murphy, SN, Smoller, JW, Perlis, RH
JournalBiological psychiatry
Date Published2014/01/19
ISSN0006-3223
Abstract

While antidepressant treatment response appears to be partially heritable, no consistent genetic associations have been identified. Large, rare copy number variants (CNVs) play a role in other neuropsychiatric diseases, so we assessed their association with treatment-resistant depression (TRD).

URLhttp://linkinghub.elsevier.com/retrieve/pii/S0006-3223(14)00006-7
DOI10.1016/j.biopsych.2013.10.028
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/24529801?dopt=Abstract