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PloS one DOI:10.1371/journal.pone.0085893

Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21.

Publication TypeJournal Article
Year of Publication2014
AuthorsHamrefors, V, Hedblad, B, Hindy, G, Smith, JG, Almgren, P, Engström, G, Sjögren, M, Gränsbo, K, Orho-Melander, M, Melander, O
JournalPloS one
Volume9
Issue1
Pagese85893
Date Published2014/01/22
Abstract

Genetic predisposition for cardiovascular disease (CVD) is likely to be modified by environmental exposures. We tested if the associated risk of CVD and CVD-mortality by the single nucleotide polymorphism rs4977574 on chromosome 9p21 is modified by life-style factors.

URLhttp://dx.plos.org/10.1371/journal.pone.0085893
DOI10.1371/journal.pone.0085893
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/24465769?dopt=Abstract