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Cell DOI:10.1016/j.cell.2013.12.012

What we talk about when we talk about fat.

Publication TypeJournal Article
Year of Publication2014
AuthorsRosen, ED, Spiegelman, BM
JournalCell
Volume156
Issue1-2
Pages20-44
Date Published2014 Jan 16
ISSN1097-4172
KeywordsAdipocytes, Adipogenesis, Animals, Humans, Lipid Metabolism, Obesity
Abstract

There has been an upsurge of interest in the adipocyte coincident with the onset of the obesity epidemic and the realization that adipose tissue plays a major role in the regulation of metabolic function. The past few years, in particular, have seen significant changes in the way that we classify adipocytes and how we view adipose development and differentiation. We have new perspective on the roles played by adipocytes in a variety of homeostatic processes and on the mechanisms used by adipocytes to communicate with other tissues. Finally, there has been significant progress in understanding how these relationships are altered during metabolic disease and how they might be manipulated to restore metabolic health.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S0092-8674(13)01546-8
DOI10.1016/j.cell.2013.12.012
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/24439368?dopt=Abstract

Alternate JournalCell
PubMed ID24439368
PubMed Central IDPMC3934003
Grant ListR01 DK085171 / DK / NIDDK NIH HHS / United States
R01 DK087092 / DK / NIDDK NIH HHS / United States