What we talk about when we talk about fat.

Cell
Authors
Keywords
Abstract

There has been an upsurge of interest in the adipocyte coincident with the onset of the obesity epidemic and the realization that adipose tissue plays a major role in the regulation of metabolic function. The past few years, in particular, have seen significant changes in the way that we classify adipocytes and how we view adipose development and differentiation. We have new perspective on the roles played by adipocytes in a variety of homeostatic processes and on the mechanisms used by adipocytes to communicate with other tissues. Finally, there has been significant progress in understanding how these relationships are altered during metabolic disease and how they might be manipulated to restore metabolic health.

Year of Publication
2014
Journal
Cell
Volume
156
Issue
1-2
Pages
20-44
Date Published
2014 Jan 16
ISSN
1097-4172
URL
DOI
10.1016/j.cell.2013.12.012
PubMed ID
24439368
PubMed Central ID
PMC3934003
Links
Grant list
R01 DK085171 / DK / NIDDK NIH HHS / United States
R01 DK087092 / DK / NIDDK NIH HHS / United States