|Publication Type||Journal Article|
|Year of Publication||2014|
|Authors||Malik, R, Bevan, S, Nalls, MA, Holliday, EG, Devan, WJ, Cheng, YC, Ibrahim-Verbaas, CA, Verhaaren, BF, Bis, JC, Joon, AY, Destefano, AL, Fornage, M, Psaty, BM, Ikram, MA, Launer, LJ, van Duijn, CM, Sharma, P, Mitchell, BD, Rosand, J, Meschia, JF, Levi, C, Rothwell, PM, Sudlow, C, Markus, HS, Seshadri, S, Dichgans, M, Wellcome Trust Case Control Consortium, 2|
|Journal||Stroke; a journal of cerebral circulation|
Genome-wide association studies have revealed multiple common variants associated with known risk factors for ischemic stroke (IS). However, their aggregate effect on risk is uncertain. We aimed to generate a multilocus genetic risk score (GRS) for IS based on genome-wide association studies data from clinical-based samples and to establish its external validity in prospective population-based cohorts.