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Trends in microbiology DOI:10.1016/j.tim.2013.12.002

Bacterial toxins and small molecules elucidate endosomal trafficking.

Publication TypeJournal Article
Year of Publication2013
AuthorsSlater, LH, Clatworthy, AE, Hung, DT
JournalTrends in microbiology
Date Published2013/12/23
ISSN0966-842X
Abstract

Bacterial toxins and small molecules are useful tools for studying eukaryotic cell biology. In a recent issue of PNAS, Gillespie and colleagues describe a novel small molecule inhibitor of bacterial toxins and virus trafficking through the endocytic pathway, 4-bromobenzaldehyde N-(2,6-dimethylphenyl)semicarbazone (EGA), that prevents transport from early to late endosomes.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S0966-842X(13)00249-7
DOI10.1016/j.tim.2013.12.002
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/24370463?dopt=Abstract