Poly-combing the genome for RNA.

Nat Struct Mol Biol
Authors
Keywords
Abstract

An unresolved question in mammalian epigenetic regulation is how ubiquitously expressed chromatin-modifying complexes such as Polycomb group complex 2 (PRC2) find their specific target sites across an intricate choreography of localization events in time and space. Two recent studies now provide critical new insights into an intriguing genome-wide role for RNA in PRC2 regulation.

Year of Publication
2013
Journal
Nat Struct Mol Biol
Volume
20
Issue
12
Pages
1344-6
Date Published
2013 Dec
ISSN
1545-9985
URL
DOI
10.1038/nsmb.2728
PubMed ID
24304912
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