Poly-combing the genome for RNA.
Nat Struct Mol Biol
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Abstract | An unresolved question in mammalian epigenetic regulation is how ubiquitously expressed chromatin-modifying complexes such as Polycomb group complex 2 (PRC2) find their specific target sites across an intricate choreography of localization events in time and space. Two recent studies now provide critical new insights into an intriguing genome-wide role for RNA in PRC2 regulation. |
Year of Publication | 2013
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Journal | Nat Struct Mol Biol
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Volume | 20
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Issue | 12
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Pages | 1344-6
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Date Published | 2013 Dec
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ISSN | 1545-9985
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URL | |
DOI | 10.1038/nsmb.2728
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PubMed ID | 24304912
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