|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Conway, KL, Kuballa, P, Song, JH, Patel, KK, Castoreno, AB, Yilmaz, OH, Jijon, HB, Zhang, M, Aldrich, LN, Villablanca, EJ, Peloquin, JM, Goel, G, Lee, IA, Mizoguchi, E, Shi, HN, Bhan, AK, Shaw, SY, Schreiber, SL, Virgin, HW, Shamji, AF, Stappenbeck, TS, Reinecker, HC, Xavier, RJ|
& Aims: Intestinal epithelial cells aid in mucosal defense by providing a physical barrier against entry of pathogenic bacteria and secreting anti-microbial peptides (AMPs). Autophagy is an important component of immune homeostasis. However, little is known about its role in specific cell types during bacterial infection in vivo. We investigated the role of autophagy in the response of intestinal epithelial and antigen-presenting cells to Salmonella infection in mice.