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Cell Stem Cell DOI:10.1016/j.stem.2013.06.006

Browsing (Epi)genomes: a guide to data resources and epigenome browsers for stem cell researchers.

Publication TypeJournal Article
Year of Publication2013
AuthorsKarnik, R, Meissner, A
JournalCell Stem Cell
Volume13
Issue1
Pages14-21
Date Published2013 Jul 03
ISSN1875-9777
KeywordsDatabases, Factual, Epigenomics, Genome, Human, Humans, Internet, Software, Stem Cell Research
Abstract

Over the past years we have witnessed an explosion in the generation of freely available genome-wide data sets, including maps of various histone modifications, transcription factor binding, DNase hypersensitivity, and DNA methylation, which provide valuable resources for data validation, exploration, and hypothesis generation. The goal of this review is to provide the reader with information on where to find many of the data sets and how to utilize the various (epi)genome browsers for display and initial analysis. We provide selected examples to highlight key features and demonstrate the application of these browsers to stem cell biology.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S1934-5909(13)00264-6
DOI10.1016/j.stem.2013.06.006
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/23827707?dopt=Abstract

Alternate JournalCell Stem Cell
PubMed ID23827707
PubMed Central IDPMC3750740
Grant ListP01 GM099117 / GM / NIGMS NIH HHS / United States
U01 ES017155 / ES / NIEHS NIH HHS / United States
P01GM099117 / GM / NIGMS NIH HHS / United States
U01ES017155 / ES / NIEHS NIH HHS / United States