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Cell DOI:10.1016/j.cell.2019.02.015

Genetics of Common, Complex Coronary Artery Disease.

Publication TypeJournal Article
Year of Publication2019
AuthorsMusunuru, K, Kathiresan, S
JournalCell
Volume177
Issue1
Pages132-145
Date Published2019 Mar 21
ISSN1097-4172
Abstract

Coronary artery disease represents the leading cause of death worldwide, sparing no nation, ethnicity, or economic stratum. Coronary artery disease is partly heritable. While enormous effort has been devoted to understanding the genetic basis of coronary artery disease and other common, complex cardiovascular diseases, key challenges have emerged in gene discovery, in understanding how DNA variants connect to function, and in translation of genetics to the clinic. We discuss these challenges as well as promising opportunities to bring the work closer to fruition.

DOI10.1016/j.cell.2019.02.015
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/30901535?dopt=Abstract

Alternate JournalCell
PubMed ID30901535