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Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.
|Publication Type||Journal Article|
|Authors||Gerard, B., Lee MD 4th, Dandapani S., Duvall JR, Fitzgerald ME, Kesavan S., Lowe JT, Marié JC, Pandya BA, Suh BC, O'Shea MW, Dombrowski M., Hamann D., Lemercier B., Murillo T., Akella LB, Foley MA, and Marcaurelle LA|
|Abstract||A diversity-oriented synthesis (DOS) strategy was developed for the synthesis of stereochemically diverse fused-ring systems containing a pyran moiety. Each scaffold contains an amine and methyl ester for further diversification via amine capping and amide coupling. Scaffold diversity was evaluated in comparison to previously prepared scaffolds by a shape-based principal moments of inertia (PMI) analysis.|
|Year of Publication||2013|
|Journal||The Journal of organic chemistry|
|Date Published (YYYY/MM/DD)||2013/06/07|