Scientific Publications

Moving toward personalized medicine in castration-resistant prostate cancer.

Publication TypeJournal Article
AuthorsVan Allen, EM, and Pomerantz M.
AbstractRecent advances in research technologies have allowed improved molecular characterization of castration-resistant prostate cancer (CRPC). These efforts hold promise for development of therapies that target alterations unique to an individual patient's prostate cancer. Targets include androgens and the androgen receptor pathway, pathways associated with hormone-resistant disease, and the immune system. In aggregate, this will allow physicians to choose treatments based on a particular tumor profile. As these approaches are developed, CRPC treatment is becoming an example of truly personalized medicine.
Year of Publication2012
JournalThe Urologic clinics of North America
Volume39
Issue4
Pages483-90
Date Published (YYYY/MM/DD)2012/11/01
ISSN Number0094-0143
DOI10.1016/j.ucl.2012.07.005
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/23084525?dopt=Abstract