|Publication Type||Journal Article|
|Year of Publication||2012|
|Authors||Van Allen, EM, Pomerantz, M|
|Journal||Urol Clin North Am|
|Date Published||2012 Nov|
|Keywords||Androgens, Antineoplastic Agents, Carrier Proteins, Disease Progression, Humans, Immunotherapy, Male, Neoplasms, Hormone-Dependent, Precision Medicine, Prostatic Neoplasms, Receptors, Androgen|
Recent advances in research technologies have allowed improved molecular characterization of castration-resistant prostate cancer (CRPC). These efforts hold promise for development of therapies that target alterations unique to an individual patient's prostate cancer. Targets include androgens and the androgen receptor pathway, pathways associated with hormone-resistant disease, and the immune system. In aggregate, this will allow physicians to choose treatments based on a particular tumor profile. As these approaches are developed, CRPC treatment is becoming an example of truly personalized medicine.
|Alternate Journal||Urol. Clin. North Am.|