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Wiley Interdiscip Rev RNA DOI:10.1002/wrna.1134

Computational analysis of noncoding RNAs.

Publication TypeJournal Article
Year of Publication2012
AuthorsWashietl, S, Will, S, Hendrix, DA, Goff, LA, Rinn, JL, Berger, B, Kellis, M
JournalWiley Interdiscip Rev RNA
Volume3
Issue6
Pages759-78
Date Published2012 Nov-Dec
ISSN1757-7012
KeywordsAnimals, Computational Biology, Data Mining, Databases, Nucleic Acid, Genomics, Humans, MicroRNAs, Molecular Sequence Annotation, Nucleic Acid Conformation, RNA Folding, RNA, Untranslated
Abstract

Noncoding RNAs have emerged as important key players in the cell. Understanding their surprisingly diverse range of functions is challenging for experimental and computational biology. Here, we review computational methods to analyze noncoding RNAs. The topics covered include basic and advanced techniques to predict RNA structures, annotation of noncoding RNAs in genomic data, mining RNA-seq data for novel transcripts and prediction of transcript structures, computational aspects of microRNAs, and database resources.

URLhttp://dx.doi.org/10.1002/wrna.1134
DOI10.1002/wrna.1134
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/22991327?dopt=Abstract

Alternate JournalWiley Interdiscip Rev RNA
PubMed ID22991327
PubMed Central IDPMC3472101
Grant ListRC1 CA147187 / CA / NCI NIH HHS / United States
1RC1CA147187 / CA / NCI NIH HHS / United States