|Publication Type||Journal Article|
|Year of Publication||2012|
|Authors||Brandes, A, Lun, DS, Ip, K, Zucker, J, Colijn, C, Weiner, B, Galagan, JE|
Bacteria have evolved the ability to efficiently and resourcefully adapt to changing environments. A key means by which they optimize their use of available nutrients is through adjustments in gene expression with consequent changes in enzyme activity. We report a new method for drawing environmental inferences from gene expression data. Our method prioritizes a list of candidate carbon sources for their compatibility with a gene expression profile using the framework of flux balance analysis to model the organism's metabolic network.