Scratching the Surface of Immunotherapeutic Targets in Neuroblastoma.
Cancer Cell
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Abstract | In this issue of Cancer Cell, Bosse et al. report GPC2 as a therapeutic target in neuroblastoma. They show that GPC2 is selectively expressed on the cell surface of neuroblastoma and is a dependency in this disease. Moreover, they demonstrate the therapeutic potential of an antibody-drug conjugate targeting GPC2. |
Year of Publication | 2017
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Journal | Cancer Cell
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Volume | 32
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Issue | 3
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Pages | 271-273
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Date Published | 2017 09 11
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ISSN | 1878-3686
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DOI | 10.1016/j.ccell.2017.08.011
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PubMed ID | 28898689
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Grant list | R01 NS088355 / NS / NINDS NIH HHS / United States
R35 CA210030 / CA / NCI NIH HHS / United States
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