Scratching the Surface of Immunotherapeutic Targets in Neuroblastoma.

Cancer Cell
Authors
Keywords
Abstract

In this issue of Cancer Cell, Bosse et al. report GPC2 as a therapeutic target in neuroblastoma. They show that GPC2 is selectively expressed on the cell surface of neuroblastoma and is a dependency in this disease. Moreover, they demonstrate the therapeutic potential of an antibody-drug conjugate targeting GPC2.

Year of Publication
2017
Journal
Cancer Cell
Volume
32
Issue
3
Pages
271-273
Date Published
2017 09 11
ISSN
1878-3686
DOI
10.1016/j.ccell.2017.08.011
PubMed ID
28898689
Links
Grant list
R01 NS088355 / NS / NINDS NIH HHS / United States
R35 CA210030 / CA / NCI NIH HHS / United States