Scientific Publications

GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity.

Publication TypeJournal Article
AuthorsFomina-Yadlin, D., Kubicek S., Vetere A., He KH, Schreiber SL, and Wagner BK
AbstractExpression of insulin in terminally differentiated non-beta cell types in the pancreas could be important to treating type-1 diabetes. Previous findings led us to hypothesize involvement of kinase inhibition in induction of insulin expression in pancreatic alpha cells.
Year of Publication2012
JournalPloS one
Volume7
Issue1
Pagese28808
Date Published (YYYY/MM/DD)2012/01/01
DOI10.1371/journal.pone.0028808
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/22242153?dopt=Abstract