Scientific Publications

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.

Publication TypeJournal Article
AuthorsCho, YJ, Tsherniak A., Tamayo P., Santagata S., Ligon A., Greulich H., Berhoukim R., Amani V., Goumnerova L., Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A., Delattre O., Kool M., Ligon K., Meyerson M., Mesirov J. P., and Pomeroy SL
AbstractMedulloblastomas are heterogeneous tumors that collectively represent the most common malignant brain tumor in children. To understand the molecular characteristics underlying their heterogeneity and to identify whether such characteristics represent risk factors for patients with this disease, we performed an integrated genomic analysis of a large series of primary tumors.
Year of Publication2011
JournalJournal of clinical oncology : official journal of the American Society of Clinical Oncology
Volume29
Issue11
Pages1424-30
Date Published (YYYY/MM/DD)2011/04/10
ISSN Number0732-183X
DOI10.1200/JCO.2010.28.5148
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/21098324?dopt=Abstract