Scientific Publications

A one-bead, one-stock solution approach to chemical genetics: part 2.

Publication TypeJournal Article
AuthorsClemons, PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, and Foley MA
AbstractChemical genetics provides a systematic means to study biology using small molecules to effect spatial and temporal control over protein function. As complementary approaches, phenotypic and proteomic screens of structurally diverse and complex small molecules may yield not only interesting individual probes of biological function, but also global information about small molecule collections and the interactions of their members with biological systems.
Year of Publication2001
JournalChemistry & biology
Volume8
Issue12
Pages1183-95
Date Published (YYYY/MM/DD)2001/12/01
ISSN Number1074-5521
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/11755397?dopt=Abstract