|Publication Type||Journal Article|
|Year of Publication||2011|
|Authors||Bernstein, BE, Liu, CL, Humphrey, EL, Perlstein, EO, Schreiber, SL|
Although eukaryotic genomes are generally thought to be entirely chromatin-associated, the activated PHO5 promoter in yeast is largely devoid of nucleosomes. We systematically evaluated nucleosome occupancy in yeast promoters by immunoprecipitating nucleosomal DNA and quantifying enrichment by microarrays.