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Nat Rev Cancer DOI:10.1038/nrc2044

The Connectivity Map: a new tool for biomedical research.

Publication TypeJournal Article
Year of Publication2007
AuthorsLamb, J
JournalNat Rev Cancer
Volume7
Issue1
Pages54-60
Date Published2007 01
ISSN1474-175X
KeywordsAlgorithms, Animals, Biomedical Research, Computational Biology, Gene Expression Regulation, Genome, Humans, Information Services, Information Storage and Retrieval, Models, Biological, Models, Genetic, Neoplasms, Phenotype, Software
Abstract

The ultimate objective of biomedical research is to connect human diseases with the genes that underlie them and drugs that treat them. But this remains a daunting task, and even the most inspired researchers still have to resort to laborious screens of genetic or chemical libraries. What if at least some parts of this screening process could be systematized and centralized? And hits found and hypotheses generated with something resembling an internet search engine? These are the questions the Connectivity Map project set out to answer.

URLhttp://dx.doi.org/10.1038/nrc2044
DOI10.1038/nrc2044
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/17186018?dopt=Abstract

Alternate JournalNat. Rev. Cancer
PubMed ID17186018