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Journal of biology DOI:10.1186/jbiol56

Multilevel regulation of growth rate in yeast revealed using systems biology.

Publication TypeJournal Article
Year of Publication2012
AuthorsRamanathan, A, Schreiber, SL
JournalJournal of biology
Volume6
Issue2
Pages3
Date Published2012/01/06
ISSN1478-5854
Abstract

The effect of changing growth rates on the transcriptome, proteome and metabolome has been systematically studied. Measurements made under varying nutrient conditions, corresponding to biochemical pathways that correlate primarily with growth rate, reveal a central role for mitochondrial metabolism and the TOR (target of rapamycin) signaling pathway.

URLhttp://www.jbiol.com/content/6/2/3
DOI10.1186/jbiol56
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/17472733?dopt=Abstract