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J Org Chem DOI:10.1021/jo070502w

Synthesis of kaempferitrin.

Publication TypeJournal Article
Year of Publication2007
AuthorsUrgaonkar, S, Shaw, JT
JournalJ Org Chem
Volume72
Issue12
Pages4582-5
Date Published2007 Jun 08
ISSN0022-3263
KeywordsGlycosylation, Kaempferols, Phloroglucinol
Abstract

A short synthesis of Kaempferitrin (1), a 3,7-diglycosylflavone, is reported. Key features include the synthesis of a protected form of kaempferol in which all four hydroxy groups are differentiated and the first bis-glycosylation of a dihydroxyflavone. This synthesis will allow the preparation of derivatives for further explorations into the origins of this compound's biological activity.

URLhttp://dx.doi.org/10.1021/jo070502w
DOI10.1021/jo070502w
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/17497804?dopt=Abstract

Alternate JournalJ. Org. Chem.
PubMed ID17497804
Grant ListP50 GM069721 / GM / NIGMS NIH HHS / United States
R03 AI062905-01 / AI / NIAID NIH HHS / United States