Scientific Publications

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

Publication TypeJournal Article
AuthorsPlenge, RM, Seielstad M., Padyukov L., Lee AT, Remmers EF, Ding B., Liew A., Khalili H., Chandrasekaran A., Davies LR, Li W., Tan AK, Bonnard C., Ong RT, Thalamuthu A., Pettersson S., Liu C., Tian C., Chen WV, Carulli JP, Beckman EM, Altshuler D., Alfredsson L., Criswell LA, Amos CI, Seldin MF, Kastner DL, Klareskog L., and Gregersen PK
AbstractRheumatoid arthritis has a complex mode of inheritance. Although HLA-DRB1 and PTPN22 are well-established susceptibility loci, other genes that confer a modest level of risk have been identified recently. We carried out a genomewide association analysis to identify additional genetic loci associated with an increased risk of rheumatoid arthritis.
Year of Publication2007
JournalThe New England journal of medicine
Volume357
Issue12
Pages1199-209
Date Published (YYYY/MM/DD)2007/09/20
ISSN Number0028-4793
DOI10.1056/NEJMoa073491
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/17804836?dopt=Abstract