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The New England journal of medicine DOI:10.1056/NEJMoa073491

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

Publication TypeJournal Article
Year of Publication2007
AuthorsPlenge, RM, Seielstad, M, Padyukov, L, Lee, AT, Remmers, EF, Ding, B, Liew, A, Khalili, H, Chandrasekaran, A, Davies, LR, Li, W, Tan, AK, Bonnard, C, Ong, RT, Thalamuthu, A, Pettersson, S, Liu, C, Tian, C, Chen, WV, Carulli, JP, Beckman, EM, Altshuler, D, Alfredsson, L, Criswell, LA, Amos, CI, Seldin, MF, Kastner, DL, Klareskog, L, Gregersen, PK
JournalThe New England journal of medicine
Volume357
Issue12
Pages1199-209
Date Published2007/09/20
ISSN0028-4793
Abstract

Rheumatoid arthritis has a complex mode of inheritance. Although HLA-DRB1 and PTPN22 are well-established susceptibility loci, other genes that confer a modest level of risk have been identified recently. We carried out a genomewide association analysis to identify additional genetic loci associated with an increased risk of rheumatoid arthritis.

URLhttp://dx.doi.org/10.1056/NEJMoa073491
DOI10.1056/NEJMoa073491
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/17804836?dopt=Abstract