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Genome biology DOI:10.1186/gb-2008-9-3-r50

Cross-kingdom patterns of alternative splicing and splice recognition.

Publication TypeJournal Article
Year of Publication2008
AuthorsMcGuire, AM, Pearson, MD, Neafsey, DE, Galagan, JE
JournalGenome biology
Volume9
Issue3
PagesR50
Date Published2008/01/01
ISSN1474-7596
Abstract

Variations in transcript splicing can reveal how eukaryotes recognize intronic splice sites. Retained introns (RIs) commonly appear when the intron definition (ID) mechanism of splice site recognition inconsistently identifies intron-exon boundaries, and cassette exons (CEs) are often caused by variable recognition of splice junctions by the exon definition (ED) mechanism. We have performed a comprehensive survey of alternative splicing across 42 eukaryotes to gain insight into how spliceosomal introns are recognized.

URLhttp://genomebiology.com/content/9/3/R50
DOI10.1186/gb-2008-9-3-r50
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/18321378?dopt=Abstract