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PloS one DOI:10.1371/journal.pone.0002812

Conserved secondary structures in Aspergillus.

Publication TypeJournal Article
Year of Publication2008
AuthorsMcGuire, AM, Galagan, JE
JournalPloS one
Volume3
Issue7
Pagese2812
Date Published2008/07/30
Abstract

Recent evidence suggests that the number and variety of functional RNAs (ncRNAs as well as cis-acting RNA elements within mRNAs) is much higher than previously thought; thus, the ability to computationally predict and analyze RNAs has taken on new importance. We have computationally studied the secondary structures in an alignment of six Aspergillus genomes. Little is known about the RNAs present in this set of fungi, and this diverse set of genomes has an optimal level of sequence conservation for observing the correlated evolution of base-pairs seen in RNAs.

URLhttp://dx.plos.org/10.1371/journal.pone.0002812
DOI10.1371/journal.pone.0002812
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/18665251?dopt=Abstract