Scientific Publications

High-throughput screens for fluorescent dye discovery.

Publication TypeJournal Article
AuthorsLjosa, V., and Carpenter AE
AbstractA recent screen of a combinatorial library of fluorescent compounds discovered fluorescent dyes that were able to distinguish myoblasts from differentiated myotubes. New fluorescent dyes that respond to biologically relevant changes in cell state or type are useful as stains in a wide variety of biological experiments, including high-throughput screens for chemical and genetic regulators. Combining this approach with microscopy imaging is likely to be even more powerful and might lead to the discovery of new dyes with interesting and useful properties.
Year of Publication2008
JournalTrends in biotechnology
Volume26
Issue10
Pages527-30
Date Published (YYYY/MM/DD)2008/10/01
ISSN Number0167-7799
DOI10.1016/j.tibtech.2008.06.008
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/18706725?dopt=Abstract