|Publication Type||Journal Article|
|Year of Publication||2008|
|Authors||Daniels, R, Volkman, SK, Milner, DA, Mahesh, N, Neafsey, DE, Park, DJ, Rosen, D, Angelino, E, Sabeti, PC, Wirth, DF, Wiegand, RC|
Single nucleotide polymorphism (SNP) genotyping provides the means to develop a practical, rapid, inexpensive assay that will uniquely identify any Plasmodium falciparum parasite using a small amount of DNA. Such an assay could be used to distinguish recrudescence from re-infection in drug trials, to monitor the frequency and distribution of specific parasites in a patient population undergoing drug treatment or vaccine challenge, or for tracking samples and determining purity of isolates in the laboratory during culture adaptation and sub-cloning, as well as routine passage.