|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Garber, M, Guttman, M, Clamp, M, Zody, MC, Friedman, N, Xie, X|
|Journal||Bioinformatics (Oxford, England)|
Comparing the genomes from closely related species provides a powerful tool to identify functional elements in a reference genome. Many methods have been developed to identify conserved sequences across species; however, existing methods only model conservation as a decrease in the rate of mutation and have ignored selection acting on the pattern of mutations.