Scientific Publications

microRNA expression during trophectoderm specification.

Publication TypeJournal Article
AuthorsViswanathan, SR, Mermel CH, Lu J., Lu CW, Golub T. R., and Daley GQ
AbstractSegregation of the trophectoderm from the inner cell mass of the embryo represents the first cell-fate decision of mammalian development. Transcription factors essential for specifying trophectoderm have been identified, but the role of microRNAs (miRNAs) in modulating this fate-choice has been largely unexplored. We have compared miRNA expression in embryonic stem cell (ESC)-derived trophectoderm and in staged murine embryos to identify a set of candidate miRNAs likely to be involved in trophectoderm specification.
Year of Publication2009
JournalPloS one
Volume4
Issue7
Pagese6143
Date Published (YYYY/MM/DD)2009/07/03
DOI10.1371/journal.pone.0006143
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/19582159?dopt=Abstract