|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Wang, Q, Schreiber, SL|
A copper-mediated aerobic coupling reaction enables direct amidation of heterocycles or aromatics having weakly acidic C-H bonds with a variety of nitrogen nucleophiles. These reactions provide efficient access to many biologically important skeletons, including ones with the potential to serve as inhibitors of HMTs.