Scientific Publications

Aziridines as intermediates in diversity-oriented syntheses of alkaloids.

Publication TypeJournal Article
AuthorsTaylor, AM, and Schreiber SL
AbstractThe efficient synthesis of small molecules that collectively comprise optimal small-molecule screening collections is an important goal. With this in mind, we have used N-alkyl aziridines in a regio- and stereochemically controlled synthesis of polycyclic heterocycles based on nucleophilic ring opening and subsequent intramolecular cyclization.
Year of Publication2009
JournalTetrahedron letters
Volume50
Issue26
Pages3230-3233
Date Published (YYYY/MM/DD)2009/07/02
ISSN Number0040-4039
DOI10.1016/j.tetlet.2009.02.034
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/20046991?dopt=Abstract