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PloS one DOI:10.1371/journal.pone.0008979

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

Publication TypeJournal Article
Year of Publication2010
AuthorsKim, SY, Dunn, IF, Firestein, R, Gupta, P, Wardwell, L, Repich, K, Schinzel, AC, Wittner, B, Silver, SJ, Root, DE, Boehm, JS, Ramaswamy, S, Lander, ES, Hahn, WC
JournalPloS one
Volume5
Issue2
Pagese8979
Date Published2010/02/01
Abstract

Aberrant beta-catenin signaling plays a key role in several cancer types, notably colon, liver and breast cancer. However approaches to modulate beta-catenin activity for therapeutic purposes have proven elusive to date.

URLhttp://dx.plos.org/10.1371/journal.pone.0008979
DOI10.1371/journal.pone.0008979
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/20126544?dopt=Abstract