You are here

Stroke; a journal of cerebral circulation DOI:10.1161/STROKEAHA.109.563502

Hyperlipidemia and reduced white matter hyperintensity volume in patients with ischemic stroke.

Publication TypeJournal Article
Year of Publication2010
AuthorsJimenez-Conde, J, Biffi, A, Rahman, R, Kanakis, A, Butler, C, Sonni, S, Massasa, E, Cloonan, L, Gilson, A, Capozzo, K, Cortellini, L, Ois, A, Cuadrado-Godia, E, Rodriguez-Campello, A, Furie, KL, Roquer, J, Rosand, J, Rost, NS
JournalStroke; a journal of cerebral circulation
Volume41
Issue3
Pages437-42
Date Published2010/03/01
ISSN0039-2499
Abstract

White matter hyperintensity (WMH), or leukoaraiosis, is a radiologic finding generally assumed to reflect diseased small cerebral vasculature. WMH has significant functional impact through its relation to cognitive decline and risk of ischemic and hemorrhagic stroke. Accumulating evidence suggests that some manifestations of small-vessel disease such as intracerebral hemorrhage are associated with low levels of cholesterol. We sought to determine the relation between hyperlipidemia and WMH severity in patients with acute ischemic stroke (AIS).

URLhttp://stroke.ahajournals.org/cgi/pmidlookup?view=long&pmid=20133919
DOI10.1161/STROKEAHA.109.563502
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/20133919?dopt=Abstract