Scientific Publications

Stereochemical and skeletal diversity arising from amino propargylic alcohols.

Publication TypeJournal Article
AuthorsPizzirani, D., Kaya T., Clemons PA, and Schreiber SL
AbstractAn efficient synthetic pathway to the possible stereoisomers of skeletally diverse heterocyclic small molecules is presented. The change in shape brought about by different intramolecular cyclizations of diastereoisomeric amino propargylic alcohols is quantified using principal moment-of-inertia (PMI) shape analysis.
Year of Publication2010
JournalOrganic letters
Volume12
Issue12
Pages2822-5
Date Published (YYYY/MM/DD)2010/06/18
ISSN Number1523-7060
DOI10.1021/ol100914b
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/20481457?dopt=Abstract