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Critical reviews in biochemistry and molecular biology DOI:10.3109/10409238.2010.538663

Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches.

Publication TypeJournal Article
Year of Publication2011
AuthorsGomez, JE, Clatworthy, A, Hung, DT
JournalCritical reviews in biochemistry and molecular biology
Volume46
Issue1
Pages41-66
Date Published2011/02/01
ISSN1040-9238
Abstract

Classical genetic approaches for studying bacterial pathogenesis have provided a solid foundation for our current understanding of microbial physiology and the interactions between pathogen and host. During the past decade however, advances in several arenas have expanded the ways in which the biology of pathogens can be studied. This review discussed the impact of these advances on bacterial genetics, including the application of genomics and chemical biology to the study of pathogenesis.

DOI10.3109/10409238.2010.538663
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/21250782?dopt=Abstract