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Cell stem cell DOI:10.1016/j.stem.2011.10.014

Guiding DNA methylation.

Publication TypeJournal Article
Year of Publication2011
AuthorsMeissner, A
JournalCell stem cell
Volume9
Issue5
Pages388-90
Date Published2011/11/04
ISSN1934-5909
Abstract

How DNA methyltransferases, with their limited target specificity, establish cell-type-specific epigenetic patterns is poorly understood. Schübeler and colleagues (Lienert et al., 2011) now show that methylation-determining regions (MDRs) within promoter regions are sufficient to recapitulate endogenous patterns and dynamics of DNA methylation.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S1934-5909(11)00494-2
DOI10.1016/j.stem.2011.10.014
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/22056134?dopt=Abstract