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Mycology DOI:10.1080/21501203.2011.606851

Approaches to Fungal Genome Annotation.

Publication TypeJournal Article
Year of Publication2011
AuthorsHaas, BJ, Zeng, Q, Pearson, MD, Cuomo, CA, Wortman, JR
JournalMycology
Volume2
Issue3
Pages118-141
Date Published2011/10/03
ISSN2150-1203
Abstract

Fungal genome annotation is the starting point for analysis of genome content. This generally involves the application of diverse methods to identify features on a genome assembly such as protein-coding and non-coding genes, repeats and transposable elements, and pseudogenes. Here we describe tools and methods leveraged for eukaryotic genome annotation with a focus on the annotation of fungal nuclear and mitochondrial genomes. We highlight the application of the latest technologies and tools to improve the quality of predicted gene sets. The Broad Institute eukaryotic genome annotation pipeline is described as one example of how such methods and tools are integrated into a sequencing center's production genome annotation environment.

DOI10.1080/21501203.2011.606851
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/22059117?dopt=Abstract