| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Myers, SA, Wright, J, Peckner, R, Kalish, BT, Zhang, F, Carr, SA |
| Journal | Nat Methods |
| Date Published | 2018 May 07 |
| ISSN | 1548-7105 |
| Abstract | Regulation of gene expression is primarily controlled by changes in the proteins that occupy genes' regulatory elements. We developed genomic locus proteomics (GLoPro), in which we combine CRISPR-based genome targeting, proximity labeling, and quantitative proteomics to discover proteins associated with a specific genomic locus in native cellular contexts. |
| DOI | 10.1038/s41592-018-0007-1 |
| Pubmed | |
| Alternate Journal | Nat. Methods |
| PubMed ID | 29735997 |
Nat Methods DOI:10.1038/s41592-018-0007-1
Discovery of proteins associated with a predefined genomic locus via dCas9-APEX-mediated proximity labeling.
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