A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone.

Genet Med
Authors
Keywords
Abstract

PurposeTelephone disclosure of genetic test results can improve access to services. To date, studies of its impact have focused on return of Mendelian risk information, principally hereditary cancer syndromes.MethodsIn a multisite trial of Alzheimer disease genetic risk disclosure, asymptomatic adults were randomized to receive test results in person or via telephone. Primary analyses examined patient outcomes 12 months after disclosure.ResultsData from 257 participants showed that telephone disclosure occurred 7.4 days sooner and was 30% shorter, on average, than in-person disclosure (both P 

Year of Publication
2018
Journal
Genet Med
Volume
20
Issue
1
Pages
132-141
Date Published
2018 01
ISSN
1530-0366
DOI
10.1038/gim.2017.103
PubMed ID
28726810
PubMed Central ID
PMC5897910
Links
Grant list
P30 AG053760 / AG / NIA NIH HHS / United States
M01 RR000533 / RR / NCRR NIH HHS / United States
P30 AG013846 / AG / NIA NIH HHS / United States
U19 HD077671 / HD / NICHD NIH HHS / United States
K01 HG009173 / HG / NHGRI NIH HHS / United States
U01 HG006500 / HG / NHGRI NIH HHS / United States
R01 HG002213 / HG / NHGRI NIH HHS / United States
M01 RR010284 / RR / NCRR NIH HHS / United States
UL1 TR001102 / TR / NCATS NIH HHS / United States