HDAC Inhibitors Finally Open Up: Chromatin Accessibility Signatures of CTCL.

Cancer Cell
Authors
Keywords
Abstract

In this issue of Cancer Cell, Qu et al. describe the chromatin accessibility profiles of cutaneous T cell lymphoma, with dynamic assessments of response and resistance to histone deacetylase inhibitor therapy. Their "personal regulome" analysis framework reveals chromatin features that may be predictive of clinical response to epigenetic therapy.

Year of Publication
2017
Journal
Cancer Cell
Volume
32
Issue
1
Pages
1-3
Date Published
2017 07 10
ISSN
1878-3686
DOI
10.1016/j.ccell.2017.06.008
PubMed ID
28697338
Links
Grant list
K99 CA190861 / CA / NCI NIH HHS / United States