Complete synthesis of 3'-sialyl-N-acetyllactosamine by regioselective transglycosylation.

FEBS Lett
Authors
Keywords
Abstract

Transglycolytic synthesis of 3'-sialyl-N-acetyllactosamine by sequential use of beta-galactosidase from Bacillus circulans and trans-sialidase from Trypanosoma cruzi was described. These reactions depicted the first complete synthesis of a biologically important oligosaccharide with high regioselectivity avoiding use of glycosyltransferases and NDP sugars.

Year of Publication
1996
Journal
FEBS Lett
Volume
399
Issue
3
Pages
203-6
Date Published
1996 Dec 16
ISSN
0014-5793
PubMed ID
8985145
Links