Complete synthesis of 3'-sialyl-N-acetyllactosamine by regioselective transglycosylation.
FEBS Lett
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| Abstract | Transglycolytic synthesis of 3'-sialyl-N-acetyllactosamine by sequential use of beta-galactosidase from Bacillus circulans and trans-sialidase from Trypanosoma cruzi was described. These reactions depicted the first complete synthesis of a biologically important oligosaccharide with high regioselectivity avoiding use of glycosyltransferases and NDP sugars. |
| Year of Publication | 1996
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| Journal | FEBS Lett
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| Volume | 399
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| Issue | 3
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| Pages | 203-6
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| Date Published | 1996 Dec 16
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| ISSN | 0014-5793
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| PubMed ID | 8985145
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