Purification of gramicidin A.

Anal Biochem
Authors
Keywords
Abstract

A simple chromatographic purification of the naturally occurring ion channel-forming pentadecapeptide gramicidin A (gA) is presented. This procedure allows gA to be isolated in gram quantities from the commercially available mixture of isomers after chromatography on silica gel. The gramicidin A obtained in this manner is greater than 95% pure as determined by 1HNMR, HPLC, and amino acid analysis.

Year of Publication
1990
Journal
Anal Biochem
Volume
184
Issue
1
Pages
100-3
Date Published
1990 Jan
ISSN
0003-2697
PubMed ID
1690956
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