From knowing to controlling: a path from genomics to drugs using small molecule probes.

Science
Authors
Keywords
Abstract

The National Cancer Institute Initiative in Chemical Genetics is designed to encourage the development of small molecular probes. The probes are useful for activating or inactivating protein functions, thereby providing resources that help discern the functions of gene products in normal and disease cells, as well as in tissues. This initiative includes "ChemBank," a suite of informatics tools and databases aimed at promoting the development and use of chemical genetics by scientists worldwide. The information generated with such tools should provide a critical link from genomic discovery to drug development.

Year of Publication
2003
Journal
Science
Volume
300
Issue
5617
Pages
294-5
Date Published
2003 Apr 11
ISSN
1095-9203
DOI
10.1126/science.1083395
PubMed ID
12690189
Links