Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages.

Immunity
Authors
Keywords
Abstract

Mutations in methyl-CpG-binding protein 2 (MECP2) underlie most cases of Rett Syndrome, a neurodevelopmental disorder with neurological and somatic impairments. In this issue of Immunity, Cronk et al. (2015) find that macrophages in MeCP2-deficient mice are abnormal in number, as well as in glucocorticoid, hypoxia, and inflammatory responses.

Year of Publication
2015
Journal
Immunity
Volume
42
Issue
4
Pages
600-2
Date Published
2015 Apr 21
ISSN
1097-4180
DOI
10.1016/j.immuni.2015.04.002
PubMed ID
25902477
Links