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Immunity DOI:10.1016/j.immuni.2015.04.002

Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages.

Publication TypeJournal Article
Year of Publication2015
AuthorsSchafer, DP, Stevens, B
JournalImmunity
Volume42
Issue4
Pages600-2
Date Published2015 Apr 21
ISSN1097-4180
KeywordsAnimals, CpG Islands, Epigenesis, Genetic, Female, Humans, Macrophages, Peritoneal, Male, Methyl-CpG-Binding Protein 2, Microglia, Rett Syndrome
Abstract

Mutations in methyl-CpG-binding protein 2 (MECP2) underlie most cases of Rett Syndrome, a neurodevelopmental disorder with neurological and somatic impairments. In this issue of Immunity, Cronk et al. (2015) find that macrophages in MeCP2-deficient mice are abnormal in number, as well as in glucocorticoid, hypoxia, and inflammatory responses.

DOI10.1016/j.immuni.2015.04.002
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/25902477?dopt=Abstract

Alternate JournalImmunity
PubMed ID25902477