The Various Metabolic Sources of Histone Acetylation.

Trends Endocrinol Metab
Authors
Abstract

Glucose-derived acetyl-CoA levels directly impact histone acetylation, linking the energetic status of the cell to its epigenome. Two recent reports showed that other carbon sources can contribute to the acetyl-CoA pool used for histone acetylation, highlighting the metabolic plasticity that allows cells to respond to nutrient availability.

Year of Publication
2017
Journal
Trends Endocrinol Metab
Volume
28
Issue
2
Pages
85-87
Date Published
2017 Feb
ISSN
1879-3061
DOI
10.1016/j.tem.2016.11.001
PubMed ID
27863854
Links