The Various Metabolic Sources of Histone Acetylation.
Trends Endocrinol Metab
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Abstract | Glucose-derived acetyl-CoA levels directly impact histone acetylation, linking the energetic status of the cell to its epigenome. Two recent reports showed that other carbon sources can contribute to the acetyl-CoA pool used for histone acetylation, highlighting the metabolic plasticity that allows cells to respond to nutrient availability. |
Year of Publication | 2017
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Journal | Trends Endocrinol Metab
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Volume | 28
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Issue | 2
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Pages | 85-87
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Date Published | 2017 Feb
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ISSN | 1879-3061
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DOI | 10.1016/j.tem.2016.11.001
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PubMed ID | 27863854
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