scTrends: A living review of commercial single-cell and spatial 'omic technologies.

Cell genomics
Authors
Abstract

Understanding the rapidly evolving landscape of single-cell and spatial omic technologies is crucial for advancing biomedical research and drug development. We provide a living review of both mature and emerging commercial platforms, highlighting key methodologies and trends shaping the field. This review spans from foundational single-cell technologies such as microfluidics and plate-based methods to newer approaches like combinatorial indexing; on the spatial side, we consider next-generation sequencing and imaging-based spatial transcriptomics. Finally, we highlight emerging methodologies that may fundamentally expand the scope for data generation within pharmaceutical research, creating opportunities to discover and validate novel drug mechanisms. Overall, this review serves as a critical resource for navigating the commercialization and application of single-cell and spatial omic technologies in pharmaceutical and academic research.

Year of Publication
2024
Journal
Cell genomics
Volume
4
Issue
12
Pages
100723
Date Published
12/2024
ISSN
2666-979X
DOI
10.1016/j.xgen.2024.100723
PubMed ID
39667347
Links