Finding the right friends: Stromal composition influences TLS formation in ovarian cancer.
Cancer cell
| Authors | |
| Abstract | In this issue of Cancer Cell, MacFawn et al. reveal that tertiary lymphoid structures (TLSs) in high-grade serous ovarian cancer (HGSOC) vary significantly by anatomical site. They highlight a distinct stromal composition associated with TLS formation, with cancer-educated mesenchymal stem cells (CA-MSCs) inversely linked to TLS activity and patient prognosis. |
| Year of Publication | 2024
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| Journal | Cancer cell
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| Date Published | 10/2024
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| ISSN | 1878-3686
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| DOI | 10.1016/j.ccell.2024.10.004
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| PubMed ID | 39486409
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